Israeli researchers eliminate most cancer cells in bone marrow using RNA therapy system

A recent study from Tel Aviv University tests the effectiveness of a cancer treatment using an RNA-based drug delivered to cells via specific lipids. Photo: Tima Miroshnichenko/Pexels.A recent study from Tel Aviv University tests the effectiveness of a cancer treatment using an RNA-based drug delivered to cells via specific lipids. Photo: Tima Miroshnichenko/Pexels.

A group of scientists from Tel Aviv University managed to develop nanoparticles from lipids that are very effective in eliminating Carcinogenic cells in the marrow. Each of these nanoparticles contains RNA molecules that silence the CKAP5 gene, associated with the cytoskeleton.

By inhibiting this protein, the disease cells cannot divide and eventually die. It was proven that this treatment was 90% effective in eliminating cancer cells in the blood of multiple myeloma, in the laboratory. In addition, they reflected 60% effectiveness in treating patients at the Rabin Medical Center.

“The targeted drug delivery system we developed is the first to effectively reach cancer cells within the bone marrow,” stated the scientists behind this discovery.

The group was led by Dan Peer. Peer is a pioneering researcher in the development of genetic treatments and head of the Nanomedicine Laboratory of the Faculty of Biomedicine at TAU.

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One thought on “Israeli researchers eliminate most cancer cells in the bone marrow using an RNA therapy system”
  1. If Israel could spend more on medical technology and not on weapons to defend itself from enemies, the world would be a little happier!!!

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